G n' J FormerMember over 6 years ago in reply to Dreamthief The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Learn the signs and symptoms of metastasis, how you can make yourself as comfortable as possible, and tips for managing end-of-life symptoms. Its a hormone therapy for breast cancer. If youd like to know about using Femara for these purposes, talk with your doctor. Both medications belong to a group of drugs called aromatase inhibitors. The list below includes factors to consider. Femara, which works by lowering your estrogen level, is prescribed for females* whove gone through menopause. But if it contains estrogen, it may interact with Femara treatment. The following drugs should not be used while youre taking Femara: There arent any herbs or supplements that have been specifically reported to interact with Femara. It also helps keep the drug from harming the environment. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. If you have questions about whether its safe for you to drive or operate machinery during your treatment, talk with your doctor or pharmacist. Your doctor can recommend other treatments, besides Femara, that are safe for you to use. Femara can stay in your system after you stop taking the drug. Lymph node surgery helps doctors determine, Knowing the early signs of breast cancer can help a person seek prompt treatment and improve their chance of survival. Here are a few tips that might help guide your discussion: Remember, your doctor and other healthcare professionals are available to help you. This also includes the release of bisphosphonates from bone surfaces that end up in the bloodstream, because they can't attach themselves to the bone cells and are simply unused. This was common in clinical studies of the drug. Like most drugs, Femara may cause mild or serious side effects. Its a type of drug called an aromatase inhibitor. Learn more about some of the side effects that Femara may cause. If you experience fatigue during your Femara treatment that doesnt go away or thats bothersome, talk with your doctor. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Some people may have an allergic reaction to Femara. (Day 1 of your menstrual cycle is the first day of your period.) * However, its sometimes used off-label for this use. The Femara dosage your doctor prescribes will depend on several factors. Chemotherapy describes traditional drugs used to treat cancer. Last updated on Sep 27, 2021. There's no way to completely predict or prevent breast cancer. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. You shouldnt drive or operate machinery until you know how the drug will affect you. The most common cause of ovulation problems that result in infertility is polycystic ovary syndrome (PCOS). But Femara is also sometimes used to treat infertility that doesnt have an obvious cause. Letrozole is approved to be used alone or with other drugs to treat: Breast cancer in postmenopausal women who have any of the following types of breast cancer--. Letrozole's terminal elimination half-life is about 2 days and steady-state plasma concentration after daily 2.5 mg dosing is reached in 2-6 weeks. If you miss a dose, do not take a double dose the next day. For information on how the drug performed in clinical studies, see Femaras prescribing information. If you have a certain type of breast cancer, your doctor might suggest Femara (letrozole) as a treatment option. No, the Food and Drug Administration (FDA) hasnt approved Femara for use in bodybuilding. In fact, aromatase inhibitors such as Femara are recommended in current guidelines for people with HR+ breast cancer. If you have questions about the risks of Femara use in pregnancy, talk with your doctor. This means that Femara will no longer be in your body when you ovulate or conceive. Some may be a better fit for you than others. However, there are steps you can take to reduce your risk. Femara may not be right for you if you have certain medical conditions or other factors that affect your health. If youre concerned about side effects from stopping Femara treatment after 5 years, talk with your doctor. When you stop taking letrozole, most persistent side effects should improve within a week or 10 days, and as long as you have taken it for at least 5 years, then letrozole should continue to reduce the risk of breast cancer coming back for many years after you stop taking it. This medicine is available only with your doctor's prescription. But try to always stick to the same time each day. Spotting may occur with Femara use. If you have questions about any symptoms after stopping Femara, talk with your doctor. How to Reduce Your Risk of Breast Cancer: 10 Lifestyle Recommendations, Symptoms of Late Stage Metastatic Breast Cancer, What to Know and Consider Before Having Prophylactic Mastectomy. (To learn more, see Is Femara used for infertility? right above.) Some people taking Femara may experience weight gain. If youd like to know more about how Femara and Arimidex compare with each other, see this detailed breakdown. These symptoms could be life threatening and require immediate medical care. Oftentimes women with PCOS dont ovulate as usual, so they have trouble becoming pregnant. Keep in mind that side effects of a drug can depend on: Your doctor or pharmacist can tell you more about the potential side effects of Femara. Then, you can share this information with your doctor. After five years, last September, my GP said that I should stop takingt the Letrozole, but could not answer any of my questions, e.g. bone, muscle, or joint pain*. These effects are called interactions. But both drugs are usually taken for 5 days at the start of your menstrual cycle. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about how to pay for your prescription, talk with your doctor or pharmacist. Some side effects, such as osteoporosis (weakened bones), will not get better on their own, even after you stop taking Femara. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Learn more. Generally it takes four to five half-lives for a drug to be eliminated from the body, so in the case of Arimidex this would be 150 to 300 hours, or six to 12 days. Taking medications, vaccines, foods, and other things with a certain drug can affect how the drug works. When you get Femara from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Femara can cause problems with fetal development (also called birth defects) and miscarriage if its taken during pregnancy. Healthline Media does not provide medical advice, diagnosis, or treatment. If youre concerned about hair loss while taking Femara, talk with your doctor. Taking Femara can cause high cholesterol in some people. Costs of prescription drugs can vary depending on many factors. For example, they may order imaging tests to see if your cancer tumors are shrinking. Although theyre not common side effects, in some cases, Femara can cause anxiety or depression. What should be considered before taking Femara? Most of these side effects may go away within a few days or a couple of weeks. Infertility is often caused by problems with ovulation (when eggs are released from your ovaries). If youd like to know about using Femara for this purpose, talk with your doctor. Keeping cool with a fan or removing layers of clothing during hot flash episodes. A hot shower or bath may also provide some headache relief. Your doctor might ask you to take Femara on either cycle days 3 to 7 or cycle days 5 to 9. your doctor may . The aromatase enzyme helps make estrogen from other hormones called androgens. Common side effects can be like menopause symptomsand include hot flushes, difficulty sleeping, tiredness and low mood. But sometimes the drug is used off-label to treat infertility in females* with PCOS. Symptoms of a severe allergic reaction can include swelling under your skin, typically in your eyelids, lips, hands, or feet. However, if you think youre having a medical emergency, you should call 911 or your local emergency number. However, if you have severe symptoms, immediately call 911 (or your local emergency number) or go to the nearest emergency room. Femara is a brand-name prescription drug thats approved to treat breast cancer in females* whove gone through menopause. The FDA website provides several useful tips on medication disposal. Taking letrozole for long periods of time has been associated with an increased risk of bone fractures and heart side effects. For information about the difference between sex and gender, see this article. You should not become pregnant or breastfeed for at least 3 weeks after your last dose of Femara. They can suggest ways to help manage this side effect. More specifically, Femara is a type of hormone therapy called an aromatase inhibitor. And talk with your doctor about ways to help improve your energy level during treatment. You should always consult your doctor or another healthcare professional before taking any medication. Femara should not be used during pregnancy or while breastfeeding. Its not chemotherapy, which is a type of cancer drug that most commonly causes hair loss. But this side effect wasnt reported in studies. You can also find information on the drugs strength, form, and more. After menopause, your body produces less estrogen, which can weaken your bones. Not taking letrozole for the recommended time may increase the risk of your breast cancer coming back. But sometimes Femara is used off-label for other conditions. This dosage is 1 tablet once daily. There are also some things you can do to help minimize loss of bone strength while youre taking Femara. Can diet help improve depression symptoms? What are the more common side effects of Femara? How do Femaras side effects compare with those of other cancer drugs? If you no longer need to take Femara and have leftover medication, its important to dispose of it safely. When talking with your doctor, you may want to ask the following questions: To learn more about breast cancer and its treatment options, sign up for Healthlines breast cancer newsletter. Based on when your period begins, your doctor will advise you when to start treatment. Clomiphene is approved to treat infertility in females. * An allergic reaction is possible after taking Femara. Femara isnt FDA-approved to treat infertility, but sometimes its used off-label for this purpose in females. Here are a few other questions you may want to ask your doctor about Femara: In addition, you can learn about breast cancer and its treatment options by subscribing to Healthlines breast cancer newsletter. Also describe any vitamins, herbs, or supplements you use. Adjuvant treatment of breast cancer is treatment thats taken to reduce the risk of the cancer coming back after surgery. Also, if you experience fatigue, extreme tiredness, or dizziness while taking Femara, you shouldnt drive or operate heavy machinery. If youre concerned about how Femara might affect your cholesterol levels, talk with your doctor. Some that are rare (occurring in less than 10% of patients) are not listed here. They work by lowering estrogen levels within your body, which helps stop the growth of breast cancer. Letrozole's terminal elimination half-life is about 2 days and steady-state plasma concentration after daily 2.5 mg dosing is reached in 2-6 weeks. Femara may cause hair loss in some people. Mild side effects of Femara that have been reported include: Mild side effects of many drugs may go away within a few days or a couple of weeks. Using more than this can lead to serious side effects. If you experience side effects that dont go way or interfere with your daily life, talk with your doctor or pharmacist. If you think you could be pregnant or have pregnancy symptoms, tell your doctor before you start taking Femara. Stopping Femara isnt known to cause any withdrawal symptoms. (Enzymes help chemical reactions in your body to happen.). For more information about Femara, including details about the types of breast cancer it treats, see this in-depth article on the drug. This date is typically 1 year from the date they dispensed the medication. Swelling caused by Femara typically occurs in your arms, feet, hands, or legs. If youre interested in finding an alternative to Femara, talk with your doctor. Your doctor can recommend treatment options other than Femara. When you take Femara to induce (cause) ovulation, the drug is cleared from your body within several days after youve stopped taking it. For details about how side effects for these drugs compare, see the Arimidex vs. letrozole section of this article. Letrozole is typically taken once a day for five days. By stopping aromatase from working, Femara lowers the amount of estrogen in your body. How long a medication remains good can depend on many factors, including how and where you store the medication. Bring someone with you to your appointment if doing so will help you feel more comfortable. Breast Cancer Treatment: Why Some Older Patients May Not Need Radiation, TV Host Samantha Harris Says her Breast Cancer Was Misdiagnosed for Months. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. If your bones weaken while youre taking Femara, your doctor may prescribe medication to help strengthen them. Cancer cells multiply quickly, but some healthy cells in your body also multiply quickly. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. It works by lowering the level of estrogen in your body. Is the ketogenic diet right for autoimmune conditions? Spotting refers to slight vaginal bleeding when you arent having your period. Call your doctor right away if you have serious side effects. Your bones rely on estrogen to keep them strong. If the side effects seem life threatening or if you think youre having a medical emergency, immediately call 911 or your local emergency number. If you find the side effects ease within the two weeks they may try you on Anastrozole or even Exemstane. These lists do not contain all the drugs that may interact with Femara. Its also worth noting that alcohol is known to increase the risk of developing breast cancer. Different interactions can cause different effects. Find answers to some commonly asked questions about Femara. What happens when you stop taking letrozole? A 2019 review of studies also found Femara to be more effective than clomiphene in treating infertility in females* with PCOS. For this use, youll usually take Femara for 5 years after youve already taken tamoxifen for 5 years following surgery to remove the cancer. If you do drink alcohol while taking Femara, you might be more likely to experience: If you plan to drink alcohol while taking Femara, talk with your doctor about how much may be safe for you to drink. Not all side effects are listed above. For this purpose, Femara is usually used to help lower the risk of the cancer coming back after its been removed by surgery. Symptoms of a severe allergic reaction can include: Call your doctor right away if you have a severe allergic reaction to Femara. Below youll find answers to some frequently asked questions about Femaras side effects. If youre concerned about weight gain while taking Femara, talk with your doctor. Letrozole is a pill, taken by mouth. So, dont be afraid to ask questions or offer feedback on your treatment. Below are examples of off-label uses for Femara. However, statistics show that many people with breast cancer have an excellent chance of. But actual success rates of Femara for achieving pregnancy or having live births depend on many factors. Femara and clomiphene are both used to induce (cause) ovulation in females* who are having trouble becoming pregnant. If letrozole stops working and your breast cancer comes back, your specialist may prescribe another hormone drug. If youre at a moderate weight, you may have fewer and less serious hot flashes. If you experienced side effects while taking Femara, those side effects may not go away for a few weeks after your last dose . Femara is a hormone therapy thats used for HR+ breast cancer. In this article, learn about, Breast cancer, which mainly affects females, is common. It can also interact with certain supplements as well as certain foods. However, alcohol can cause side effects similar to those of Femara. (Off-label use means using a drug for a condition other than the one its approved to treat.). The standard Femara dosage is the same for all types of breast cancer the drug is used to treat. These types of therapies stop estrogen from encouraging breast cancer cells to grow. If you have questions about using Femara to treat infertility, talk with your doctor. Its possible you may have side effects after stopping Femara treatment. vaginal spotting. Other drugs are available that can treat breast cancer. Over-the-counter (OTC) medications, such as acetaminophen (Tylenol) and ibuprofen (Advil), may be effective for relieving headaches. For more information about using Femara for infertility, see the section Off-label use of Femara for infertility above. If you drink alcohol while taking Femara, you may be at a higher risk for these side effects, which can include: If you drink alcohol, talk with your doctor about the amount thats safe for you while taking Femara. Femara is also sometimes used off-label to treat infertility in females with endometriosis. You may take Letrozole with or without food. If you develop serious side effects while taking Femara, call your doctor right away. It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. If you drink alcohol and youre concerned about how this might affect your condition, talk with your doctor. If you have questions or concerns about using Femara for infertility, talk with your doctor. Factors to consider include those in the list below. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. See Femaras prescribing information for details. There's no way to completely predict or prevent breast cancer. So, side effects that you have while taking Femara may continue for a few weeks after you stop using it. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Zara Risoldi Cochrane, Pharm.D., M.S., FASCP, Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system. No, you likely wont. Always check with your doctor or pharmacist before using any herbs or supplement products while youre taking Femara. Learn. You might take a look at the Calling Long Term Survivors thread, I believe there's a couple of women who have been on it for 4+ years. So, chemotherapy can affect both healthy cells and cancer cells. This use of the drug is called ovulation induction. About 90% of radiolabeled letrozole is recovered in urine. There are also some steps you can take to help strengthen your bones naturally. A medication timer may be useful, too. Prophylactic mastectomy is surgery to remove breast tissue. Will my breast cancer come back after I stop Femara treatment? Femara is also used off-label to treat infertility. If youre breastfeeding, talk with your doctor before you start taking Femara. If youre pregnant or thinking about becoming pregnant, talk with your doctor. If you have questions about Femaras success rate in treating cancer, talk with your doctor. But its not known how often this occurs in people using Femara. Can Breast Cancer Be Detected in a Complete Blood Count (CBC)? Femara is used in the following ways for early HR+ breast cancer: Femara is used in the following ways for advanced breast cancer thats either HR+ or whose hormone receptor status isnt known: * Sex and gender exist on spectrums. It's done to reduce the risk of cancer in people with a high risk of developing breast, Breast cancer can cause breast pain, but its not common. You should take Femara according to your doctors or another healthcare professionals instructions. Instead, Femara is a hormone therapy. Natco Pharma Limited. And you should continue to avoid breastfeeding for at least 3 weeks after your last dose of the drug. Learn the signs and symptoms of metastasis, how you can make yourself as comfortable as possible, and tips for managing end-of-life symptoms. The lists below describe some of the more common side effects that Femara may cause. These can include: If these changes dont ease your symptoms of hot flashes, you may need to take medication. Coming off letrozole. Healthline Media does not provide medical advice, diagnosis, or treatment. Its not known if Femara passes into breast milk. Medically reviewed by Carmen Fookes, BPharm. * For more information about using Femara for infertility, see the section Off-label use of Femara for infertility above. If youre already ovulating before taking Femara, the drug may cause more eggs than usual to mature and be released from your ovaries. But if you think youre having a medical emergency, call 911 or your local emergency number. Such drinks and foods may worsen hot flashes. In other words, it takes about 2 days for your body to get rid of half of a Femara dose. In that case, just skip the missed dose and take your next dose as scheduled. Call your doctor right away if you have bone pain. The greater the density, the stronger your bones are. Visit Medicine Assistance Tool to find programs that may help lower your cost of Femara. Femara and clomiphene are both used to stimulate ovulation in females who are having trouble becoming pregnant. For breast cancer treatment, youll usually take Femara once each day. . Do not stop taking letrozole without talking to your treatment team first. (Day 1 of your menstrual cycle is the first of your period.) Another 2019 review of studies found Femara and clomiphene to be similarly effective in treating unexplained infertility. Most people will take Femara to treat their breast cancer for at least 5 years. Treatment will be taken over five consecutive days. Letrozole lowers the levels of the female sex hormone oestrogen in the body. Below are brief descriptions of each type of breast cancer Femara is used to treat: Before taking Femara, its important to talk with your doctor about your overall health and other medical conditions you have. Femara shouldnt be taken during pregnancy. . Hormone therapies stop estrogen from encouraging breast cancer cells to grow. This may raise the chance of broken bones. Femara can cause mild or serious side effects. Dont take two doses together to make up for a missed dose. In studies, this was a common side effect reported in people taking the drug. It may also be used when someone is premenopausal and having treatment to stop the ovaries working (temporary menopause). You can take Femara with or without food. In certain situations, if Femara has stopped working for you, your doctor might ask you to stop taking the drug in order to cause a withdrawal response. This response is a hormonal shift thats caused by stopping Femara. Below are commonly used dosages, but always take the dosage your doctor prescribes. 2005-2023 Healthline Media a Red Ventures Company. Available for Android and iOS devices. In fact, aromatase inhibitors such as Femara are recommended in current guidelines for people with HR+ breast cancer. If you have fatigue or dizziness while youre taking Femara, dont drive or operate other machines. However, this particular treatment approach isnt right for everyone. Femara can interact with some other medications. The recommended length of time that letrozole is taken for will depend on your individual situation. If you have questions or concerns about this potential side effect, talk with your doctor or pharmacist. You actually will have a decrease in the effects of the Femara (letrozole) which are joint pain, hot flashes, fatigue and generalized dryness. Hormone therapy may also be used to treat hot flashes. The generic is considered to be as safe and effective as the original drug. To find out how often this side effect occurred in clinical studies, see the drugs prescribing information. And your doctor can use this information to adjust your treatment plan if needed. If you and your doctor determine that Femara is safe and effective for you, youll likely take it long term. One thing that may help is trying to stay as active as possible. Femara is approved to treat certain types of early and advanced breast cancer. Your doctor will help you to weigh potential risks and benefits of taking Femara for a long period of time. If you have osteoporosis or risk factors* for developing this condition, talk with your doctor before starting Femara. Lumpectomy and mastectomy are different types of cancer surgery that remove cancer cells from the breast. If your doctor thinks Femara has stopped working for you, talk with them about whether stopping treatment could be beneficial for you. This drug may cause weak bones. Generic forms of Femara are available. And you shouldnt become pregnant or breastfeed for at least 3 weeks after your last dose of the drug. Femara may cause fatigue (lack of energy) in some people. But you wont be able to notice it working in your body. They may suggest an over-the-counter oral antihistamine, such as Benadryl (diphenhydramine), or a topical product, such as hydrocortisone cream, to manage your symptoms. 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